bpod-mrc:

20 July 2014

Hard Hearted

As calcium builds up in tissues it gradually causes them to harden or calcify. It’s how our bodies build teeth and bones. When calcification happens in cardiovascular tissue, however, it reduces blood flow and eventually leads to heart failure. To better understand the problem, researchers have taken snapshots of calcified heart valves using a special microscope that can measure the density of a material as well as its surface features. Images like this one, where denser material appears orange, have revealed that spherical particles forming during soft-tissue calcification are composed of a form of calcium known as hydroxyapatite, which is structurally different to that found in bone. Such insights might help figure out how to break down the mineral deposits or even prevent them forming in the first place.

Written by Daniel Cossins

Image by Sergio Bertazzo from the Wellcome Image Awards 2014
Imperial College London
Originally published under a Creative Commons Licence (BY 4.0)
Research published in Nature, April 2013

You can also follow BPoD on Twitter and Facebook

Since there is no evidence of the impact of screening for diabetes, there is no evidence as to which test is best to use for screening. Options include fasting glucose, random glucose, oral glucose tolerance testing, or glycosylated hemoglobin. According to the ADA, any one of these tests (with the exception of the random glucose) is considered acceptable for screening. 
The ADA recommends low-dose aspirin for the primary prevention of coronary artery disease in patients with type 2 diabetes who have increased cardiovascular risk (i.e., 10-year risk of MI of >10%, which includes most diabetic men (over 50) and women (over 60) who have at least one additional major cardiovascular risk).
ZoomInfo
Since there is no evidence of the impact of screening for diabetes, there is no evidence as to which test is best to use for screening. Options include fasting glucose, random glucose, oral glucose tolerance testing, or glycosylated hemoglobin. According to the ADA, any one of these tests (with the exception of the random glucose) is considered acceptable for screening. 
The ADA recommends low-dose aspirin for the primary prevention of coronary artery disease in patients with type 2 diabetes who have increased cardiovascular risk (i.e., 10-year risk of MI of >10%, which includes most diabetic men (over 50) and women (over 60) who have at least one additional major cardiovascular risk).
ZoomInfo

Since there is no evidence of the impact of screening for diabetes, there is no evidence as to which test is best to use for screening. Options include fasting glucose, random glucose, oral glucose tolerance testing, or glycosylated hemoglobin. According to the ADA, any one of these tests (with the exception of the random glucose) is considered acceptable for screening. 

The ADA recommends low-dose aspirin for the primary prevention of coronary artery disease in patients with type 2 diabetes who have increased cardiovascular risk (i.e., 10-year risk of MI of >10%, which includes most diabetic men (over 50) and women (over 60) who have at least one additional major cardiovascular risk).

USMLE Step 1 Score Day

The email came today signifying an important point in my medical school career: I received my USMLE Step 1 scores and passed, which is the good news! The scores were not as high as had I hoped they would be so I will need to work extra hard this year during MS3 to prove that I do in fact know medicine and am worthy of a fantastic residency program. 

The path to becoming a great physician will continue to be full of excitement and disappointments just the same, but I hope to stay focused on the many things I still have to learn, the many people who will help me, and the many patients who will count on me to make them feel better. 

We are not our scores, even though we can’t deny how important they are to residency application success. As student doctors, we are our experiences, we are our knowledge, and we are our dedication to our patients. 

Anyone who has passed this exam knows the endless joy that comes with PASS on the score report. It’s really true, we are closer than ever to realizing our dream of becoming the physician.